Plump lips and smooth, wrinkle free skin is everybody’s dream. Nowadays it can be easily achieved with Hyaluronic acid (HA) dermal fillers.
Hyaluronic acid is naturally found throughout the human body, particularly in the eyes and connective tissues with an approximate concentration of 0.6mg/g HA in the skin.
One of its important biological activities is water retention in the dermal matrix, implying the potential of delivering or maintaining skin hydration when the skin is treated with HA.
Due to its ability to store moisture hyaluronic acid is responsible for giving skin a plump, hydrating look. It has been shown that HA may stimulate collagen production which will lead to younger looking skin.
The main limitation of HA, when it is used in its free form (not cross-linked), is a short lifetime due to the rapid enzymatic degradation in the skin. In order to increase viscosity and reduce the susceptibility to enzymatic degradation.
HA is often cross-linked by dysfunctional molecules of synthetic origin.
Once crosslinked, HA is able to stay in the dermal tissue much longer.